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Tocris
sb 505 124 Sb 505 124, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/result/sb 505 124/product/Tocris Average 95 stars, based on 1 article reviews
sb 505 124 - by Bioz Stars,
2026-05
95/100 stars
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SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptor ALK5 and as well as being a selective inhibitor of ALK4 but with less potency. SB-505124 blocks TGF-β-induced apoptosis of FaO cells and
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SB-505124 is an inhibitor of activin receptor-like kinase (ALK-5). SB-505124 is demonstrated to suppress the action of transforming growth factor-B (TGF-B) both in vitro and in vivo.
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Inhibitor of ALK4, ALK5, and ALK7 receptors. Inhibitor of ALK4, ALK5, and ALK7 receptors.
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SB505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5, ALK4 and ALK7) with potential anticancer activity. SB505124 selectively inhibits signaling from TGF-β and activin but does not inhibit other ALK family
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SB-505124 is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or
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SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.
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